Naruto Shippūden - Season 2 - Eps 42: Orochimaru vs. Jinchuriki
Naruto, in the four-tailed state, begins attacking Orochimaru with incredible force, devastating the surrounding landscape and preventing Sai and Yamato's wood clone from approaching him. The majority of Orochimaru's attacks prove to be ineffective, but Naruto also fails to kill Orochimaru as he regenerates from any injuries he sustains. Meanwhile, Kabuto advances toward Sakura and Yamato, deducing that Sasori has died. Orochimaru finally manages to strike Naruto with a sword blade from his mouth, and Sakura reacts in horror when she sees Naruto's four-tailed state.
About Naruto Shippūden

Title: Naruto Shippūden
First Air Date: 2007-02-15
Last Air Date: 2017-03-23
Status: Ended
Rating: 8.538/10 (from 8290 votes)
Language: JA
Seasons: 21
Total Episodes: 500
Network: TV Tokyo
Genres: Animation, Action & Adventure, Sci-Fi & Fantasy
Production Companies: TV Tokyo, Pierrot, Sound Box, Rakuonsha, Aniplex
Synopsis
After 2 and a half years Naruto finally returns to his village of Konoha, and sets about putting his ambitions to work. It will not be easy though as he has amassed a few more dangerous enemies, in the likes of the shinobi organization; Akatsuki.
Cast

Junko Takeuchi
Naruto Uzumaki (voice)

Noriaki Sugiyama
Sasuke Uchiha (voice)

Chie Nakamura
Sakura Haruno (voice)

Kazuhiko Inoue
Kakashi Hatake (voice)

Showtaro Morikubo
Shikamaru Nara (voice)

Satoshi Hino
Sai (voice)

Akira Ishida
Gaara (voice)

Hideo Ishikawa
Itachi Uchiha (voice)

Koichi Tochika
Neji Hyuga (voice)

Keiko Nemoto
Shizune (voice)