Naruto Shippūden - Season 2 - Eps 49: Something Important...
Kabuto fights Team Kakashi and frees Sai. However, Sai, who intends to learn more about his bond with his brother through Naruto's bond with Sasuke, betrays him. Captured, Kabuto gives a vague description of Sasuke's location to the team. Leaving Yamato's wood clone to watch over Kabuto, Team Kakashi enters Orochimaru's hideout and splits up to find Sasuke.
About Naruto Shippūden

Title: Naruto Shippūden
First Air Date: 2007-02-15
Last Air Date: 2017-03-23
Status: Ended
Rating: 8.538/10 (from 8290 votes)
Language: JA
Seasons: 21
Total Episodes: 500
Network: TV Tokyo
Genres: Animation, Action & Adventure, Sci-Fi & Fantasy
Production Companies: TV Tokyo, Pierrot, Sound Box, Rakuonsha, Aniplex
Synopsis
After 2 and a half years Naruto finally returns to his village of Konoha, and sets about putting his ambitions to work. It will not be easy though as he has amassed a few more dangerous enemies, in the likes of the shinobi organization; Akatsuki.
Cast

Junko Takeuchi
Naruto Uzumaki (voice)

Noriaki Sugiyama
Sasuke Uchiha (voice)

Chie Nakamura
Sakura Haruno (voice)

Kazuhiko Inoue
Kakashi Hatake (voice)

Showtaro Morikubo
Shikamaru Nara (voice)

Satoshi Hino
Sai (voice)

Akira Ishida
Gaara (voice)

Hideo Ishikawa
Itachi Uchiha (voice)

Koichi Tochika
Neji Hyuga (voice)

Keiko Nemoto
Shizune (voice)