Spider-Man - Season 1 - Eps 1: Night of the Lizard
Peter Parker and his college science professor Dr. Curt Conners explore neogenics as a method of limb regeneration. But while experimenting on himself, Connors accidentally becomes the Lizard, a half-man, half-reptile monstrosity that terrorizes Manhattan and subsequently kidnaps his own wife. Spider-Man's task is doubly difficult because he doesn't want to hurt the good friend he knows is trapped inside...but he must stop the inhuman beast who is out of control.
About Spider-Man

Title: Spider-Man
First Air Date: 1994-11-19
Last Air Date: 1998-01-31
Status: Canceled
Rating: 8.285/10 (from 1042 votes)
Language: EN
Seasons: 5
Total Episodes: 65
Network: Fox Kids FOX
Genres: Animation, Action & Adventure
Production Companies: Marvel Entertainment Group, Marvel Films, New World Entertainment Films, TMS Entertainment, Genesis Entertainment
Synopsis
Bitten by a neogenetic spider, Peter Parker develops spider-like superpowers. He uses these to fight crime while trying to balance it with the struggles of his personal life.
Cast

Christopher Daniel Barnes
Peter Parker / Spider-Man (voice)

Sara Ballantine
Mary Jane Watson (voice)

Jennifer Hale
Felicia Hardy (voice)

Linda Gary
Aunt May Parker (voice)

Gary Imhoff
Harry Osborn (voice)

Ed Asner
J. Jonah Jameson (voice)

Rodney Saulsberry
Joe "Robbie" Robertson (voice)

Roscoe Lee Browne
Kingpin (voice)